As the Cannabis market expands for both medical and recreational use, so does the need for standardized quality control in the industry. When it comes to Cannabis quality control there are numerous things to consider, from moisture content to pesticide use.
Moisture Content – Cannabis flower moisture content needs to be tested and controlled to: minimize the risk of mold formation; control microbiological levels; ensure proper drying, curing and storage conditions; and support product shelf life. Some manufacturing processes for marijuana quality control procedures also require a certain water content in the starting material.
Terpenoids and Cannabinoids Analysis
The degree of terpenoids and cannabinoids in the starting material determines the best choice industrial processing method and which final cannabis product will be manufactured. This analysis is normally carried out using LC-MS (Liquid Chromatography Mass Spectrometry) or GC (Gas Chromatography). LC-MS and GC demand a flow of inert gas like hydrogen or nitrogen, each of which can easily be supplied using a gas generator. Discover more about the Peak Scientific variety of gas generators for GC & LC-MS here.
Pesticides and Herbicides – As with other agricultural crops and merchandise intended for human consumption, Cannabis plants needs to be tested for herbicides and pesticides. Detecting pesticides and herbicides can be challenging as a result of complexity of cannabis material. GCMS (Gas Chromatography Mass Spectrometry) is normally used for this specific purpose.
Microbiological Screening – Medical Cannabis is usually employed for HIV and cancer patients in which the patient’s defense mechanisms has become compromised. Therefore, high microbial levels or pathogenic micro-organisms might be life-threatening. It is crucial then that several Mycotoxins and fungus types needs to be detected as part of cannabis quality control and release specifications.
Residual Solvents – Where solvents have been used as an element of Cannabis product processing, solvent residuals in the final products needs to be tested to ensure they fulfill the accepted criteria. The FDA has published zvqtob criteria for residual solvents in APIs for pharmaceutical use.
Heavy Metals – Like a number of other plants, Cannabis draws metals from your earth. It is actually therfore essential to test for Mercury, Lead, Arsen and Cadmium.
Cannabinoid Concentration – Concentration ranges for cannabinoids like THC,THCa, CBD, CBDa, CBN, CBC, CBG should match the ranges specified on the product label, according to product usage purpose, patient’s medical problem, age etc. Cannabinoid concentrations can be tested using LC-MS (Liquid Chromatography Mass Spectrometry) and HPLC (High End Liquid Chromatography) . You will find an array of Peak Scientific nitrogen gas generators designed especially for LC-MS, available here.
Terpene Concentration – Terpenes increase cannabinoids’ therapeutic effects and are acknowledged to get their own health and fitness benefits, additionally they contribute to Cannabis taste and aroma. They can be detected using GC.
Taking all of the above under consideration, it is actually clear that you will find a necessity for standarized procedures for all the Cannabis analysis and testing process in order to guarantee safe use. The safest way to supply cannabis testing laboratories with gas for their LC-MS and GC is via gas generators, which do not present the health and safety risks associated with gas cylinders.